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BN40969R-100ul
100ul
￥2360.00
交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow) 推薦應(yīng)用：WB,IHC-P,Flow-Cyt,ELISA
BN40969R-200ul
200ul
￥3490.00
交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow) 推薦應(yīng)用：WB,IHC-P,Flow-Cyt,ELISA
產(chǎn)品描述
| 英文名稱 | Oct-4B/OCT4B-190 |
| 中文名稱 | 胚胎干細(xì)胞關(guān)鍵蛋白190抗體(N端) |
| 別 名 | Oct-4B; Oct4B; Oct 4B; Oct 4B-190; Oct4B-190; POU domain, class 5, transcription factor 1; Octamer-binding transcription factor 3; Oct-3; NF-A3; Otf-3; Otf3; POU5F1. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 干細(xì)胞 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, Rat, (predicted: Dog, Pig, Cow, ) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 Flow-Cyt=1μg /Test （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 21/39kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human OCT4B-190:201-300/360 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq]. SWISS: Q01860 Gene ID: 5460 Database links: Entrez Gene: 5460 Human Entrez Gene: 18999 Mouse Omim: 164177 Human SwissProt: Q01860 Human SwissProt: P20263 Mouse Unigene: 249184 Human Unigene: 632482 Human Unigene: 646545 Human Unigene: 17031 Mouse Unigene: 161748 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. OCT4B-190蛋白能夠增強(qiáng)細(xì)胞在應(yīng)激條件下抵抗凋亡的能力。OCT4基因在干細(xì)胞的增殖、分化、應(yīng)激反應(yīng)、凋亡過程等多個生物學(xué)過程中發(fā)揮著重要的作用。 |
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